Cancer Patients' Own Cells Used to Test Treatments
2021-09-01
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1Researchers used a brain cancer patient's cells to make a model of a tumor to test treatments before using them on the body.
2The tumor model was created with 3D printing materials.
3The scientists removed a piece of the tumor from a patient with glioblastoma and used it to print a model of the tumor.
4That explanation comes from Professor Ronit Satchi-Fainaro, who led the research at Tel Aviv University in Israel.
5Glioblastoma is an aggressive form of brain cancer.
6The patient's blood is pumped through the printed tumor and then a drug or therapeutic treatment is pumped in.
7Earlier studies have used similar "bioprinting" methods to reproduce cancer environments.
8But the Tel Aviv University researchers say they are the first to print a "viable" tumor.
9Satchi-Fainaro said they have about two weeks to test the different therapies on a tumor and find a fitting treatment for the patient.
10A treatment is considered promising if the printed tumor shrinks or if it lowers metabolic activity.
11The research was released on Wednesday in the publication Science Advances.
12Glioblastoma is the most common form of brain cancer in adults.
13It spreads quickly to other parts of the brain, making it difficult to treat.
14Survival is around 40 percent in the first year and 17 percent in the second.
15That information is from the American Association of Neurological Surgeons.
16Researchers have often printed 3D tumor models to plan for surgery.
17But more recent developments have used live cells as a kind of printing substance to build up the parts of a tumor.
18Ofra Benny leads similar research at the Hebrew University of Jerusalem.
19She said using a patient's own cells to make 3D tumor models could be "a game changer in the field of personalized medicine."
20The more these 3D models are made, the better the prediction for how a treatment will work on the patient's tumor, she said.
21I'm Alice Bryant.
1Researchers used a brain cancer patient's cells to make a model of a tumor to test treatments before using them on the body. The tumor model was created with 3D printing materials. 2The scientists removed a piece of the tumor from a patient with glioblastoma and used it to print a model of the tumor. That explanation comes from Professor Ronit Satchi-Fainaro, who led the research at Tel Aviv University in Israel. 3Glioblastoma is an aggressive form of brain cancer. 4The patient's blood is pumped through the printed tumor and then a drug or therapeutic treatment is pumped in. 5Earlier studies have used similar "bioprinting" methods to reproduce cancer environments. But the Tel Aviv University researchers say they are the first to print a "viable" tumor. 6Satchi-Fainaro said they have about two weeks to test the different therapies on a tumor and find a fitting treatment for the patient. 7A treatment is considered promising if the printed tumor shrinks or if it lowers metabolic activity. 8The research was released on Wednesday in the publication Science Advances. 9Glioblastoma is the most common form of brain cancer in adults. It spreads quickly to other parts of the brain, making it difficult to treat. Survival is around 40 percent in the first year and 17 percent in the second. That information is from the American Association of Neurological Surgeons. 10Researchers have often printed 3D tumor models to plan for surgery. But more recent developments have used live cells as a kind of printing substance to build up the parts of a tumor. 11Ofra Benny leads similar research at the Hebrew University of Jerusalem. She said using a patient's own cells to make 3D tumor models could be "a game changer in the field of personalized medicine." 12The more these 3D models are made, the better the prediction for how a treatment will work on the patient's tumor, she said. 13I'm Alice Bryant. 14Reuters news reported this story. Alice Bryant adapted it for Learning English. Susan Shand was the editor. 15___________________________________________________________ 16Words in This Story 17Tumor - n. a mass of tissue found in or on the body that is made up of abnormal cells 183D printing - n. the construction of a three-dimensional object from a computer model or a digital 3D model 19Viable - adj. capable of being done or used 20Metabolic - adj. of or relating to metabolism 21Surgery - n. medical treatment in which a doctor cuts into someone's body in order to repair or remove damaged or diseased parts